Parkinson's disease epidemiology and demographics: Difference between revisions

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{{Parkinson's disease}}
{{Parkinson's disease}}


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==Overview==
==Overview==
The [[incidence]] of parkinson disease is 8 to 18.6 per 100,000 person-years. The [[prevalence]] of Parkinson disease is about 0.3% in 40 years old people and older. According to this [[prevalence]] currently we have 7.5 million people affected by this [[disease]]. The [[prevalence]] of PD can rise with age. In 40 to 49 years old people the [[prevalence]] is 41 per 100,000 and in 80 years old and older people its 1900 per 100,000 people. Some studies suggest that men have a higher risk of developing Parkinson disease than women. In the study of Stephen K. Van Den Eeden and colleges it was suggested that the [[incidence]] of [[Parkinson's disease|PD]] from higher to lower is in Hispanic, non-Hispanic whites and blacks.


==Incidence==
==Incidence==
[[Incidence]] is a more sensitive indicator than prevalence because prevalence rates can be affected by socio-ecomically driven differences in survival as well as biased by survey technique problems,<ref>{{cite journal |author=Bermejo F, Gabriel R, Vega S, Morales JM, Rocca WA, Anderson DW |title=Problems and issues with door-to-door, two-phase surveys: an illustration from central Spain |journal=Neuroepidemiology |volume=20 |issue=4 |pages=225&ndash;31 |year=2001 |pmid=11684897 |doi=}}</ref> The rates are as high as 20.5 per 100,000 in the U.S.A. <ref>{{cite journal | author = Rajput | title = Epidemiology of Parkinson's disease | journal = Can J Neurol Sci. | volume = 11  | issue = 1 | pages = 156&ndash;159 | year = 1984 | pmid = 6713314}}</ref>  A study carried out in northern California observed an age and sex corrected incidence.<ref name="VanDenEeden2003">{{cite journal | author = Van Den Eeden S, Tanner C, Bernstein A, Fross R, Leimpeter A, Bloch D, Nelson L | title = Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity. | journal = Am J Epidemiol | volume = 157 | issue = 11 | pages = 1015&ndash;22 | year = 2003 | pmid = 12777365}}</ref>
 
* The [[incidence]] of parkinson disease is 8 to 18.6 per 100,000 person-years.<ref name="pmid16713924">{{cite journal |vauthors=de Lau LM, Breteler MM |title=Epidemiology of Parkinson's disease |journal=Lancet Neurol |volume=5 |issue=6 |pages=525–35 |date=June 2006 |pmid=16713924 |doi=10.1016/S1474-4422(06)70471-9 |url=}}</ref>


==Prevalence==
==Prevalence==
Parkinson's disease is widespread, with a prevalence estimated between 100 and 250 cases per 100,000 in North America; and was 1.7 per hundred (95% CI 1.5&ndash;1.9) in China (for those aged ≥65 years).<ref>{{cite journal |author=Zhang ZX, Roman GC, Hong Z, ''et al'' |title=Parkinson's disease in China: prevalence in Beijing, Xian, and Shanghai |journal=Lancet |volume=365 |issue=9459 |pages=595&ndash;7 |year=2005 |pmid=15708103 |doi=10.1016/S0140-6736(05)17909-4}}</ref>


* The [[prevalence]] of Parkinson disease is about 0.3% in 40 years old people and older. According to this [[prevalence]] currently we have 7.5 million people affected by this [[disease]].<ref name="pmid24976103">{{cite journal |vauthors=Pringsheim T, Jette N, Frolkis A, Steeves TD |title=The prevalence of Parkinson's disease: a systematic review and meta-analysis |journal=Mov. Disord. |volume=29 |issue=13 |pages=1583–90 |date=November 2014 |pmid=24976103 |doi=10.1002/mds.25945 |url=}}</ref><ref name="pmid25044188">{{cite journal |vauthors=Ross GW, Abbott RD |title=Living and dying with Parkinson's disease |journal=Mov. Disord. |volume=29 |issue=13 |pages=1571–3 |date=November 2014 |pmid=25044188 |doi=10.1002/mds.25955 |url=}}</ref>
==Age==
==Age==
Cases of PD are reported at all ages, though it is uncommon in people younger than 40. The average age at which symptoms begin in the U.S.A. is 58&ndash;60; it is principally a disease of the elderly.


* The [[prevalence]] of PD can rise with age. In 40 to 49 years old people the [[prevalence]] is 41 per 100,000 and in 80 years old and older people its 1900 per 100,000 people.<ref name="pmid24976103">{{cite journal |vauthors=Pringsheim T, Jette N, Frolkis A, Steeves TD |title=The prevalence of Parkinson's disease: a systematic review and meta-analysis |journal=Mov. Disord. |volume=29 |issue=13 |pages=1583–90 |date=November 2014 |pmid=24976103 |doi=10.1002/mds.25945 |url=}}</ref>
==Gender==
==Gender==
Men are affected more often than women in most countries.


* Some studies suggest that men have a higher risk of developing Parkinson disease than women.<ref name="pmid16713924" /><ref name="pmid24976103">{{cite journal |vauthors=Pringsheim T, Jette N, Frolkis A, Steeves TD |title=The prevalence of Parkinson's disease: a systematic review and meta-analysis |journal=Mov. Disord. |volume=29 |issue=13 |pages=1583–90 |date=November 2014 |pmid=24976103 |doi=10.1002/mds.25945 |url=}}</ref><ref name="pmid26701996">{{cite journal |vauthors=Moisan F, Kab S, Mohamed F, Canonico M, Le Guern M, Quintin C, Carcaillon L, Nicolau J, Duport N, Singh-Manoux A, Boussac-Zarebska M, Elbaz A |title=Parkinson disease male-to-female ratios increase with age: French nationwide study and meta-analysis |journal=J. Neurol. Neurosurg. Psychiatry |volume=87 |issue=9 |pages=952–7 |date=September 2016 |pmid=26701996 |pmc=5013115 |doi=10.1136/jnnp-2015-312283 |url=}}</ref>
==Race==
==Race==
It occurs in all parts of the world, but appears to be more common in people of European ancestry than in those of African ancestry. Those of East Asian ancestry have an intermediate risk. It is more common in rural than urban areas.
 
* In the study of Stephen K. Van Den Eeden and colleges it was suggested that the [[incidence]] of [[Parkinson's disease|PD]] from higher to lower is in Hispanic, non-Hispanic whites and blacks.<ref name="pmid12777365">{{cite journal |vauthors=Van Den Eeden SK, Tanner CM, Bernstein AL, Fross RD, Leimpeter A, Bloch DA, Nelson LM |title=Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity |journal=Am. J. Epidemiol. |volume=157 |issue=11 |pages=1015–22 |date=June 2003 |pmid=12777365 |doi= |url=}}</ref>
 
==Region==
*The majority of [disease name] cases are reported in [geographical region].
 
*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].


==References==
==References==

Latest revision as of 17:58, 8 August 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.

Overview

The incidence of parkinson disease is 8 to 18.6 per 100,000 person-years. The prevalence of Parkinson disease is about 0.3% in 40 years old people and older. According to this prevalence currently we have 7.5 million people affected by this disease. The prevalence of PD can rise with age. In 40 to 49 years old people the prevalence is 41 per 100,000 and in 80 years old and older people its 1900 per 100,000 people. Some studies suggest that men have a higher risk of developing Parkinson disease than women. In the study of Stephen K. Van Den Eeden and colleges it was suggested that the incidence of PD from higher to lower is in Hispanic, non-Hispanic whites and blacks.

Incidence

  • The incidence of parkinson disease is 8 to 18.6 per 100,000 person-years.[1]

Prevalence

  • The prevalence of Parkinson disease is about 0.3% in 40 years old people and older. According to this prevalence currently we have 7.5 million people affected by this disease.[2][3]

Age

  • The prevalence of PD can rise with age. In 40 to 49 years old people the prevalence is 41 per 100,000 and in 80 years old and older people its 1900 per 100,000 people.[2]

Gender

  • Some studies suggest that men have a higher risk of developing Parkinson disease than women.[1][2][4]

Race

  • In the study of Stephen K. Van Den Eeden and colleges it was suggested that the incidence of PD from higher to lower is in Hispanic, non-Hispanic whites and blacks.[5]

Region

  • The majority of [disease name] cases are reported in [geographical region].
  • [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].

References

  1. 1.0 1.1 de Lau LM, Breteler MM (June 2006). "Epidemiology of Parkinson's disease". Lancet Neurol. 5 (6): 525–35. doi:10.1016/S1474-4422(06)70471-9. PMID 16713924.
  2. 2.0 2.1 2.2 Pringsheim T, Jette N, Frolkis A, Steeves TD (November 2014). "The prevalence of Parkinson's disease: a systematic review and meta-analysis". Mov. Disord. 29 (13): 1583–90. doi:10.1002/mds.25945. PMID 24976103.
  3. Ross GW, Abbott RD (November 2014). "Living and dying with Parkinson's disease". Mov. Disord. 29 (13): 1571–3. doi:10.1002/mds.25955. PMID 25044188.
  4. Moisan F, Kab S, Mohamed F, Canonico M, Le Guern M, Quintin C, Carcaillon L, Nicolau J, Duport N, Singh-Manoux A, Boussac-Zarebska M, Elbaz A (September 2016). "Parkinson disease male-to-female ratios increase with age: French nationwide study and meta-analysis". J. Neurol. Neurosurg. Psychiatry. 87 (9): 952–7. doi:10.1136/jnnp-2015-312283. PMC 5013115. PMID 26701996.
  5. Van Den Eeden SK, Tanner CM, Bernstein AL, Fross RD, Leimpeter A, Bloch DA, Nelson LM (June 2003). "Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity". Am. J. Epidemiol. 157 (11): 1015–22. PMID 12777365.

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