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{{Choriocarcinoma}}
{{Gestational trophoblastic neoplasia}}
{{CMG}}
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==Overview==
==Overview==
Gestational trophoblastic neoplasia patients can present with history of previous pregnancies including [[hydatidiform mole]] ([[Hydatidiform mole|molar pregnancy]]) and [[miscarriage]], history of previous [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]], and [[Medical sign|signs]] and [[Symptom|symptoms]] that may suggest [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]. Symptoms of choriocarcinoma include [[vaginal bleeding]], passing of [[Tissue (biology)|tissue]] resembling a “bunch of grapes” from the [[vagina]], and [[Abdomen|abdominal]] distension.
==History==
When obtaining history from a [[patient]] with suspected gestational trophoblastic neoplasia, specific areas of focus include:
* History of previous [[pregnancies]], including [[hydatidiform mole]] ([[Hydatidiform mole|molar pregnancy]]) and [[miscarriage]]
* History of previous [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]
* [[Reproductive system|Reproductive]] factors that may increase the risk of [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]
* A family history of [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]
* [[Medical sign|Signs]] and [[Symptom|symptoms]] that may suggest [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]


==History and Symptoms==
==Symptoms==
* [[vaginal bleeding]]
===Early Symptoms of Gestational Trophoblastic Neoplasia===
* [[shortness of breath]]
* [[Vaginal bleeding]]<ref name="xxx">Signs and symptoms of gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/signs-and-symptoms/?region=ns Accessed on October 10, 2015</ref>
* [[hemoptysis]] (coughing up blood)
* [[Nausea]] and [[vomiting]]
* [[chest pain]]
* Passing of  [[Tissue (biology)|tissue]] resembling a “bunch of grapes” from the [[vagina]]
 
* Absent [[fetal]] movement during [[pregnancy]]
Signs and symptoms of gestational trophoblastic disease
* [[Abdomen|Abdominal]] distension
 
===Rare Symptoms of Gestational Trophoblastic Neoplasia===
* vaginal bleeding
* [[Headache]]
* swelling of the abdomen
* [[Edema ]]of the [[Hand|hands]] and feet
* With a hydatidiform mole, the abdomen and uterus may grow at a much faster rate than with a normal pregnancy.
* [[Abdomen|Abdominal]] or [[Pelvis|pelvic]] pain
* ovarian cysts (luteoma)
* [[Vaginal discharge]]
* nausea and vomiting
* Overactive [[thyroid gland]] ([[hyperthyroidism]]) that causes:
* Some women have a condition called hyperemesis gravidarum, which causes nausea and vomiting that is often much worse than what may occur during a normal pregnancy.
:* [[Tachycardia]]
* passing of  tissue resembling a “bunch of grapes” from the vagina
:* [[Sweating]]
* lack of fetal movement during pregnancy
:* Shaking
 
:* Heat intolerance
 
:* [[Fever]]
 
===Late Symptoms of Gestational Trophoblastic Neoplasia===
Rare signs and symptoms of GTD are:
* [[Hemoptysis]]
 
* Dry [[cough]]
* anemia (if bleeding is severe or lasts for a long time)
* [[Chest pain]]
* pre-eclampsia, a condition characterized by:
* Trouble [[breathing]]
* high blood pressure
* [[Headache]]
* abnormal amounts of protein in the urine
* [[Dizziness]]
* headache
* [[Jaundice]]
* swelling of the hands and feet
* [[Paralysis]]
 
* [[Seizure]]
* overactive thyroid gland (hyperthyroidism) that causes:
* [[Dysarthria]] and [[dysphasia]]
* rapid heartbeat
* [[Visual system|Vision]] problems
* warm skin
* [[Lump]] in the [[vagina]]
* sweating
* shaking
* feeling “too hot”
 
* abdominal or pelvic pain
* vaginal discharge
* fever
 
Late signs and symptoms
* coughing up blood
* dry cough
* chest pain
* trouble breathing
* headache
* dizziness
* yellowing of the skin or eyes (jaundicejaundiceA condition in which the skin and whites of the eyes become yellow and urine is dark yellow.)
* gradual loss of the ability to move a body part (paralysis)
* seizure
* trouble speaking
* vision problems
* lump in the vagina
 


==References==
==References==
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[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Gynecology]]
[[Category:Surgery]]

Latest revision as of 20:06, 19 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]Sabawoon Mirwais, M.B.B.S, M.D.[3]

Overview

Gestational trophoblastic neoplasia patients can present with history of previous pregnancies including hydatidiform mole (molar pregnancy) and miscarriage, history of previous gestational trophoblastic disease (GTD), and signs and symptoms that may suggest gestational trophoblastic disease (GTD). Symptoms of choriocarcinoma include vaginal bleeding, passing of tissue resembling a “bunch of grapes” from the vagina, and abdominal distension.

History

When obtaining history from a patient with suspected gestational trophoblastic neoplasia, specific areas of focus include:

Symptoms

Early Symptoms of Gestational Trophoblastic Neoplasia

Rare Symptoms of Gestational Trophoblastic Neoplasia

Late Symptoms of Gestational Trophoblastic Neoplasia

References

  1. ↑ Signs and symptoms of gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/signs-and-symptoms/?region=ns Accessed on October 10, 2015

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