Uterine cancer differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Differentiating Uterine cancer from other Diseases

  • In early disease, uterine cancer must be differentiated from other diseases causing endometrial thickening:
  • benign endometrial proliferation
  • endometrial hyperplasia
  • endometrial polyp
  • submucosal uterine leiomyoma
  • Differential considerations for advanced lesions include:
  • uterine sarcoma(s)
  • endometrial stromal sarcoma (ESS)
  • leiomyosarcoma of the uterus
  • malignant mixed Mullerian tumour (MMMT) of the uterus
  • uterine lymphoma: rare
  • primary uterine lymphoma
  • secondary uterine involvement with lymphoma
  • cervical cancer with uterine invasion
  • metastasis to the uterus from a non gynaecologcial malignancy: rare

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