Toxic leukoencephalopathy

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Toxic leukoencephalopathy
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Toxic leukoencephalopathy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884

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Toxic leukoencephalopathy or toxic spongiform leukoencephalopathy is a condition that is characterized by progressive damage (-pathy), of the white matter (leuko-) of the brain (-encephalo-) due to ingested toxins (toxic).

It is seen in some people who ingest heroin by route of smoking (chasing the dragon). It is currently unknown by what means the smoking of heroin causes the condition.

Toxic leukoencephalopathy affects white matter tracts devoted to higher cerebral function, causing clinical features that range from inattention, forgetfulness, and changes in personality to dementia, coma, and death.[1]

Obvious signs of the condition are difficulty with cognitive function and equilibrioception.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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