Thiamphenicol

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Thiamphenicol
Systematic (IUPAC) name
2,2-dichloro-N-[(1R,2R)- 1,3-dihydroxy-1- (4-methylsulfonylphenyl) propan-2-yl] acetamide
Identifiers
CAS number	15318-45-3
ATC code	J01BA02
PubChem	27200
DrugBank	?
Chemical data
Formula	C12H15Cl2NO5S
Mol. mass	356.223 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	hepatic
Half life	5.0 hours
Excretion	renal
Therapeutic considerations
Pregnancy cat.	?
Legal status	none
Routes	IV, IM, O

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Evidence Based Medicine
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Clinical Trials
Ongoing Trials on Thiamphenicol at Clinical Trials.gov Trial results on Thiamphenicol Clinical Trials on Thiamphenicol at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Thiamphenicol NICE Guidance on Thiamphenicol NHS PRODIGY Guidance FDA on Thiamphenicol CDC on Thiamphenicol
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Definitions
Definitions of Thiamphenicol
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Healthcare Provider Resources
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International
Thiamphenicol en Espanol Thiamphenicol en Francais
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Thiamphenicol is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, is insoluble in water but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Alternative names

• Dextrosulphenidol
• Thiophenicol

External links

• Overview at World Health Organization - Food and Agriculture Organization
• Raymond J, Boutros N, Bergeret M (2004). "Role of thiamphenicol in the treatment of community-acquired lung infections". Med Trop (Mars) 64 (1): 33-8. PMID 15224555.
• Marchese A, Debbia E, Tonoli E, Gualco L, Schito A (2002). "In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy.". J Chemother 14 (6): 554-61. PMID 12583545.

v • d • e Antibacterials for systemic use: amphenicols (J01B)
Chloramphenicol - Thiamphenicol - Florfenicol

v • d • e WikiDoc Research Resources for Thiamphenicol
Articles on Thiamphenicol	Most recent articles on Thiamphenicol • Most cited articles on Thiamphenicol • Review articles on Thiamphenicol • Articles on Thiamphenicol in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Thiamphenicol	Powerpoint slides on Thiamphenicol • Images of Thiamphenicol • Photos of Thiamphenicol • Podcasts & MP3s on Thiamphenicol • Videos on Thiamphenicol
Evidence Based Medicine Regarding Thiamphenicol	Cochrane Collaboration on Thiamphenicol • Bandolier on Thiamphenicol • TRIP on Thiamphenicol
Cost Effectiveness of Thiamphenicol	Cost Effectiveness of Thiamphenicol
Clinical Trials Involving Thiamphenicol	Ongoing Trials on Thiamphenicol at Clinical Trials.gov • Trial results on Thiamphenicol • Clinical Trials on Thiamphenicol at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Thiamphenicol	US National Guidelines Clearinghouse on Thiamphenicol • NICE Guidance on Thiamphenicol • NHS PRODIGY Guidance • FDA on Thiamphenicol • CDC on Thiamphenicol
Textbook Information on Thiamphenicol	Books and Textbook Information on Thiamphenicol
Pharmacology Resources on Thiamphenicol	Dosing of Thiamphenicol • Drug interactions with Thiamphenicol • Side effects of Thiamphenicol • Allergic reactions to Thiamphenicol • Overdose information on Thiamphenicol • Carcinogenicity information on Thiamphenicol • Thiamphenicol in pregnancy • Pharmacokinetics of Thiamphenicol •
Genetics, Pharmacogenomics, and Proteinomics of Thiamphenicol	Genetics of Thiamphenicol • Pharmacogenomics of Thiamphenicol • Proteomics of Thiamphenicol
Newstories on Thiamphenicol	Thiamphenicol in the news • Be alerted to news on Thiamphenicol • News trends on Thiamphenicol
Commentary on Thiamphenicol	Blogs on Thiamphenicol
Patient Resources on Thiamphenicol	Patient resources on Thiamphenicol • Discussion groups on Thiamphenicol • Patient Handouts on Thiamphenicol • Directions to Hospitals Treating Thiamphenicol • Risk calculators and risk factors for Thiamphenicol
Healthcare Provider Resources on Thiamphenicol	Symptoms of Thiamphenicol • Causes & Risk Factors for Thiamphenicol • Diagnostic studies for Thiamphenicol • Treatment of Thiamphenicol
Continuing Medical Education (CME) Programs on Thiamphenicol	CME Programs on Thiamphenicol
International Resources on Thiamphenicol	Thiamphenicol en Espanol • Thiamphenicol en Francais
Business Resources on Thiamphenicol	Thiamphenicol in the Marketplace • Patents on Thiamphenicol
Informatics Resources on Thiamphenicol	List of terms related to Thiamphenicol

de:Thiamphenicol th:ไทแอมฟีนิคอล

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