Teplizumab

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Teplizumab
Monoclonal antibody
Type?
SourceTemplate:Infobox drug/mab source
TargetCD3
Identifiers
E number{{#property:P628}}
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Teplizumab is a monoclonal antibody which it is used as an immunosuppressive drug. It is a humanized Fc-engineered monoclonal antibody also known as MGA031 and hOKT3γ1(Ala-Ala)[1][2].

References

  1. Woodle, E.S., Bluestone, J., Zivin, R., Jolliffe, L., Auger, J., Xu, D., and J. Thistlethwaite. "Humanized, nonmitogenic OKT3 antibody, huOKT3 gamma(Ala-Ala): initial clinical experience." (1998) Transplant Proc. 30:1369-1370
  2. Brown, W.M. "Anti-CD3 antibody MacroGenics Inc." (2006) Curr Opin Investig Drugs, 74:381-8.

External links

  • [2] MacroGenics, Inc.



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