Tectivirus

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Tectiviridae is classified as a class 1 virus under the Boltimore classification scheme.This family of viruses infects Gram-negative bacteria carrying drug resistance plasmids e.g. enterobacteria phage PRD1.Tectiviridae have no head-tail structure, but are capable of producing tail-like tubes of ~ 60 x 10 nm upon adsorption or after chloroform treatment. This family of viruses consist of capsids that have apical spikes extending ~20 nm and an unsual internal lipid envelope around the nucleoprotein.

The capsid is nonenveloped and has a diameter of 63 nm icosahedron structure. The capsid shells are composed of two layers, inner and outer capsid. The inner capsid shell consist of a 5-6 nm flexible shell made from a lipoprotein vesicle whereas the outer capsid is made up of a smooth, rigid 3 nm thin protein shell. The genome forms a tightly packed coil and the viral genome encodes structural proteins. The virion Mr is ~ 66 x 106 and constitutes 14-15 % of the virion by weight and 15% lipids by weight. This family of viruses have a single molecule of linear double stranded DNA of 150, 000 nucleotide long and the genome is unsegmented. Carbohydrates not detected and no information on antigenic properties.

References:

ICTVdB - The Universal Virus Database ICTVdB Management (2006). 00.068. Tectiviridae. In: ICTVdB - The Universal Virus Database, version 3. Büchen-Osmond, C. (Ed), Columbia University, New York, USA

Virus Taxonomy: Eighth Report of the International Committee on Taxonomy of Viruses H.V. Van Regenmortel, D.H.L. Bishop, M. H. Van Regenmortel, Claude M. Fauquet (Eds)

68.0.1. Tectivirus


Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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