Sulfanilamide description

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Sulfanilamide
AVC VAGINAL® FDA Package Insert
Description
Clinical Pharmacology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Description

AVC ® is a preparation for vaginal administration for the treatment of Candida albicans infections and available in the following forms:

AVC Cream

Each tube contains:

Sulfanilamide.......15.0% in a water-miscible, non-staining base made from lactose, propylene glycol, stearic acid, diglycol stearate, methylparaben, propylparaben, trolamine, and water; buffered with lactic acid to an acid pH of approximately 4.3.

Sulfanilamide is an anti-infective agent. It is p-amino-benzenesulfonamide with the chemical structure:

Sulfanilamide occurs as a white odorless crystalline powder with a slightly bitter taste and sweet aftertaste. It is slightly soluble in water, alcohol, acetone, glycerin, propylene glycol, hydrochloric acid, and solutions of potassium and sodium hydroxide. It is practically insoluble in chloroform, ether, benzene, and petroleum ether.[1]

References

  1. "AVC VAGINAL (SULFANILAMIDE) CREAM [JAZZ PHARMACEUTICALS COMMERCIAL CORP.]". Text " accessdate" ignored (help)

Adapted from the FDA Package Insert.