Strep throat natural history

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]; Aysha Anwar, M.B.B.S[3]

Overview

If left untreated, group A streptococcal pharyngitis may be self-limiting. In some cases, complications such as peritonsillar abscess, retropharyngeal abscess, mastoiditis, and cervical lymphadenitis may develop in untreated patients.[1][2][3] Less commonly, post-streptococcal glomerulonephritis, rheumatic fever, and toxic shock syndrome may develop as delayed complications. Rarely, vasculitis may occur. The prognosis of strep throat is good with treatment; complications rarely develop with adequate treatment.

Natural history

If left untreated, group A streptococcal pharyngitis may be self-limiting. In some cases, complications such as peritonsillar abscess, retropharyngeal abscess, mastoiditis, and cervical lymphadenitis may develop in untreated patients which may results in septic shock or death if they are not managed appropriately.[1][2][3] Less commonly, delayed chronic complications such as post-streptococcal glomerulonephritis, rheumatic fever, and toxic shock syndrome may develop. Rarely, vasculitis may occur.

Complications

Complications that can develop as a result of strep throat may be divided into suppurative and non-suppurative types:[1][3]

Suppurative

Images of vasculitis after Streptococcal throat infection

Case courtesy of wikidoc.org
Case courtesy of wikidoc.org


Non-suppurative

Prognosis

The prognosis of strep throat is good with treatment. Complications rarely develop with adequate treatment.[1]

References

  1. 1.0 1.1 1.2 1.3 http://www.cdc.gov/groupastrep/diseases-hcp/strep-throat.html Accessed on October 18, 2016
  2. 2.0 2.1 Rantz LA (1946). "THE NATURAL HISTORY OF HEMOLYTIC STREPTOCOCCUS SORE THROAT". Calif Med. 65 (6): 265–70. PMC 1642726. PMID 18731131.
  3. 3.0 3.1 3.2 Langlois DM, Andreae M (2011). "Group A streptococcal infections". Pediatr Rev. 32 (10): 423–9, quiz 430. doi:10.1542/pir.32-10-423. PMID 21965709.


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