Sirenomelia
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| Sirenomelia Classification and external resources | |
| Newborn Milagros Cerrón | |
| ICD-10 | Q87.2 |
| ICD-9 | 759.89 |
| MeSH | D004480 |
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Overview
Sirenomelia or Mermaid Syndrome is a very rare congenital deformity in which the legs are fused together, giving the appearance of a mermaid. This condition is found in approximately one out of every 70,000 live births[1] (about as rare as conjoined twins) and is usually fatal within a day or two of birth because of complications associated with abnormal kidney and bladder development and function. It results from a failure of normal vascular supply from the lower aorta in utero. Sirenomelia is associated with maternal diabetes.
There may be a connection to VACTERL association.
This disorder was formerly thought to be an extreme case of Caudal Regression Syndrome; however, it was reclassified to be considered a separate condition.
Notable cases
Only a handful of patients who did not have the usual kidney and bladder complications have survived this condition, three of them being:
- Tiffany Yorks of the United States (born 1988) underwent successful surgery to correct her rare congenital defect, in order to separate her legs.
- Milagros Cerrón[2][3][4][5][6] of Peru (her name meaning "miracles" in Spanish.) Yorks's surgeon, Mutaz Habal, worked in an advisory capacity during Cerrón's operation.
- Shiloh Pepin of Kennebunkport, Maine in the United States [7]
References
- ↑ Kallen B, Castilla EE, Lancaster PA, Mutchinick O, Knudsen LB, Martinez-Frias ML, Mastroiacovo P, Robert E (1992). "The cyclops and the mermaid: an epidemiological study of two types of rare malformation". J Med Genet 29 (1): 30-5. PMID 1552541.
- ↑ "'Mermaid' Girl Takes First Steps " - 26 September 2006 BBC article providing update on Milagros Cerron.
- ↑ Peru's 'miracle baby' walks on her own at San Francisco Chronicle, 20 April 2007
- ↑ [1] Milagros Cerron.
- ↑ "Peru's 'mermaid' girl doing well" at BBC News, 14 December 2005.
- ↑ Article in Daily Mail
- ↑ "Girl with Mermaid syndrome defies the odds", Portsmouth Herald, 2 August 2007
External links
- KB Taori, K Mitra, NP Ghonge, RO Gandhi, T Mammen, J Sahu. Sirenomelia Sequence (Mermaid)- Report of Three Cases. Ind J Radiol Imag 2002 12:3:399-401
- Birth Disorder Information Directory - contains many pointers to other references
- http://www.sirenomelia.org/en/
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
