Pranlukast

Pranlukast
Systematic (IUPAC) name
N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-7-yl]- 4-(4-phenylbutoxy)benzamide
Identifiers
CAS number	?
ATC code	R03DC02
PubChem	115100
Chemical data
Formula	C27H23N5O4
Mol. mass	481.503 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	Hepatic (mainly CYP3A4)
Half life	1.5 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Oral

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Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s Singulair (montelukast).

Medications of this class, which go under a variety of names according to whether one looks at the American, British or European system of nomenclature, have as their primary function the antagonism of bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.

Medications of this group are normally used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. There are several similar medications in the group; all appear to be equally effective.