|Systematic (IUPAC) name|
|Mol. mass||481.503 g/mol|
|Metabolism||Hepatic (mainly CYP3A4)|
|Half life||1.5 hours|
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Medications of this class, which go under a variety of names according to whether one looks at the American, British or European system of nomenclature, have as their primary function the antagonism of bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.
Medications of this group are normally used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. There are several similar medications in the group; all appear to be equally effective.
- ↑ 1.0 1.1 Nakade S, Ueda S, Ohno T, Nakayama K, Miyata Y, Yukawa E, Higuchi S (2006). "Population pharmacokinetics of pranlukast hydrate dry syrup in children with allergic rhinitis and bronchial asthma.". Drug Metab Pharmacokinet 21 (2): 133-9. PMID 16702733.
Drugs for obstructive airway diseases: asthma/COPD (R03)
|Adrenergics, inhalants||Short acting β2-agonists: Salbutamol/Levosalbutamol • Fenoterol • Terbutaline|
Long acting β2-agonists (LABA): Bambuterol • Clenbuterol • Formoterol • Salmeterol
other: Epinephrine • Isoproterenol • Orciprenaline
|Glucocorticoids||Beclometasone • Budesonide • Ciclesonide • Fluticasone • Mometasone|
|Anticholinergics||Ipratropium • Tiotropium|
|Mast cell stabilizers||Cromoglicate • Nedocromil|
|Xanthines||Aminophylline • Theobromine • Theophylline|
|Leukotriene antagonists||Montelukast • Pranlukast • Zafirlukast|
|Combination products||Budesonide/formoterol • Fluticasone/salmeterol • Ipratropium/salbutamol|
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