Pleurodesis
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Pleurodesis is the artificial obliteration of the pleural space. It is done to prevent recurrence of pneumothorax or pleural effusion. It can be done chemically or surgically.
Chemicals such as bleomycin, tetracycline, povidone iodine, or a slurry of talc can be introduced into the pleural space through a chest drain. The instilled chemicals cause irritation between the parietal and the visceral layers of the pleura which closes off the space between them and prevents further fluid from accumulating.
Chemical pleurodesis is a painful procedure, so patients are often premedicated with a sedative and analgesics.. A local anesthetic may be instilled into the pleural space, or an epidural catheter may be placed for anesthesia.
Surgical pleurodesis is performed via thoracotomy or thoracoscopy. This involves mechanically irritating the parietal pleura, often with a rough pad. Moreover surgical removal of parietal pleura is an effective way of achieving stable pleurodesis
Respiratory system surgeries and other procedures | |
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| Larynx and trachea | Laryngectomy - Tracheotomy - Cricothyrotomy |
| Lung and bronchus | Pneumonectomy - Bronchoscopy - Lung transplantation - Heart-lung transplant |
| Chest wall, pleura, mediastinum, and diaphragm | Thoracotomy - Thoracoscopy - Mediastinoscopy - Thoracentesis - Pleurodesis |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
