Peter Michaelis

You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.

Peter Michaelis was a German plant geneticist who focused most of his research on cytoplasm inheritance and segregation. Most of Michaelis work was carried out during the period from 1940's to 1970's at the Max Planck Institute for Plant Breeding Research in Köln/Vogelsang.

Contents 1 Research 2 Summary 3 References 4 External links

Research

Michaelis worked primarily on the inheritance and segregation of cytoplasmic mutations in Epilobium, a genus related to Oenothera. He calculated in 1955/1956 the statistical probability of the segregation of two different types of plastids under different conditions. With further research Michaelis concluded that segregation of a mutant plastid could be the only cause of the observed variegation in the species.

After this Michaelis examined thirty cases of plastid variegation where no mixed cells were found. He proposed that mutant and non-mutant plastids were still segregating in early mitotic divisions. He suggested two possible ways the plastid could influence one-another: (1) The mutant plastid might manufacture a substance that damaged the normal plastids during the maturation process. (2) The normal plastid might manufacture a substance that would allow the mutant form to develop normally.

Theory predicted that the two types could be distinguished clearly by an examination of the distribution of mutant and normal cells. Michealis found clear examples of both types of mutation in his material and published his work in 1956.

Michaelis firmly believed in complex unity in the cytoplasm, but he rejected simplistic notions such as the plasma gene or that the cause of cytoplasmic inheritance was solely due to plastids and mitochondria.

Summary

Peter Michaelis's work contributed largely to the development and understanding of organelle inheritance in Epilobium and other plants with two or more chloroplasts per cell.

References

• Michaelis, P (1951) Interactions between genes and cytoplasm in Epilobium. Cold Spring Harb Symp Quant Biol. 16:121-129.
• Michaelis, P (1954) Cytoplasmic inheritance in Epilobium and its theoretical significance. Adv Genet 6:288–402.
• Michaelis, P (1959) Cytoplasmic inheritance and the segregation of plasmagenes. X. International Congr. Genet. I. 375-385
• Michaelis, P (1966) The proof of cytoplasmic inheritance in Epilobium (a historical survey as an example for the necessary proceeding). Nucleus 9:1-16
• Michaelis, P (1971) The investigation of plasmone segregation by the pattern-analysis. Nucleus 10: 1-14

External links

• www.mpg.de
• www.mpiz-koeln.mpg.de