Perilymph
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Perilymph is an extracellular fluid located within the cochlea (part of the ear) in 2 of its 3 compartments; the scala tympani and scala vestibuli. The ionic composition of perilymph is comparable to that of plasma and cerebrospinal fluid. The major cation of perilymph is sodium.
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Perilymph vs. endolymph
The third compartment of the ear, the cochlear duct (or scala media) contains endolymph. Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells. The electric potential of endolymph is ~80-90 mV more positive than perilymph.[1]
Clinical significance
It has also been suggested that perilymph and endolymph participate in a unidirectional flow that is interrupted in Meniere's disease.
External links
References
- ↑ Konishi T, Hamrick PE, Walsh PJ (1978). "Ion transport in guinea pig cochlea. I. Potassium and sodium transport". Acta Otolaryngol. 86 (1-2): 22-34. PMID 696294.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
