Pars intermedia
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| Pars intermedia | |
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| Median sagittal through the hypophysis of an adult monkey. (Pars intermedia labeled at bottom center.) | |
| Latin | pars intermedia adenohypophyseos |
| Gray's | subject #275 1275 |
| Dorlands/Elsevier | p_07/12616939 |
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Pars intermedia is the boundary between the anterior and posterior lobes of the pituitary. It contains three types of cells - basophils, chromophobes, and colloid-filled cysts. The cysts are the remainder of Rathke’s pouch.
In human fetal life, this area produces melanocyte stimulating hormone or MSH which causes the release of melanin pigment in skin melanocytes (pigment cells). However, the pars intermedia is normally either very small or entirely absent in adulthood.
In lower vertebrates (fish, amphibians) MSH from the pars intermedia is responsible for darkening of the skin, often in response to changes in background color. This color change is due to MSH stimulating the dispersion of melanin pigment in dermal (skin) melanophore cells.
External links
- Histology at Boston University 14001loa
- Histology at Boston University 14101loa
- Histology at University of Southern California end/c_1
- Histology at University of Southern California end/c_11
- Histology at OU 38_11
- UIUC Histology Subject 991
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
