Oxygen-18

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Oxygen-18
General
Name, symbol Oxygen-18,18O
Neutrons 10
Protons 8
Nuclide data
Natural abundance 0.2%

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Oxygen-18 (18O) is a natural, stable isotope of oxygen and one of the environmental isotopes.

18O is an important precursor for the production of fluorodeoxyglucose (FDG) used in positron emission tomography (PET). Generally, in the radiopharmaceutical industry, enriched water (H218O) is bombarded with hydrogen ions in either a cyclotron or linear accelerator creating fluorine-18. This is then synthesized into FDG and injected into a patient.

Paleoclimatology

In Arctic and Antarctic ice cores, O-18 is used to retrieve the original temperatures of the precipitation during different years by analyzing the isotope ratio of the respective annual layers of ice. This happens due to the differing weights of water with the normal isotope of oxygen, and water with oxygen-18. In the 1950s, Harold Urey performed an experiment in which he mixed both normal water and water with oxygen-18 in a barrel, and then partially froze the barrel's contents. The water with oxygen-18 sunk to the bottom of the barrel and was first to freeze.

See also

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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