Oligodendroglioma surgery
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Oligodendroglioma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Oligodendroglioma surgery On the Web |
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American Roentgen Ray Society Images of Oligodendroglioma surgery |
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Risk calculators and risk factors for Oligodendroglioma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]Sujit Routray, M.D. [3]
Overview
Surgery is the first-line treatment option for patients with oligodendroglioma. However, oligodendrogliomas cannot be completely resected because of their diffusely infiltrating nature. The aim of surgery is to make a definitive diagnosis, debulk the tumor to relieve elevated intracranial pressure and reduce the tumor mass as a precursor to adjuvant treatment. CSF shunting is usually reserved for patients with hydrocephalus and includes two types of shunts: external ventricular drain-temporary shunt and internal drain-permanent shunt.
Surgery
Surgical Resection
- Surgical resection is the first-line treatment option for patients with oligodendroglioma.[1][2][3]
- Because of their diffusely infiltrating nature, oligodendrogliomas cannot be completely resected.
- The aim of surgery is to:[4]
- Make a definitive diagnosis
- Debulk the tumor to relieve elevated intracranial pressure
- Reduce the tumor mass as a precursor to adjuvant treatment
CSF Shunt
- CSF shunting is performed to relieve the pressure in the brain due to blockade in the flow of cerebrospinal fluid due to oligodendroglioma.[5]
References
- ↑ Treatment of oligodendroglioma. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/brain-and-spinal-tumours/oligodendroglioma/?region=on
- ↑ Delev D, Heiland DH, Franco P, Reinacher P, Mader I, Staszewski O; et al. (2019). "Surgical management of lower-grade glioma in the spotlight of the 2016 WHO classification system". J Neurooncol. 141 (1): 223–233. doi:10.1007/s11060-018-03030-w. PMID 30467813.
- ↑ Kawaguchi T, Sonoda Y, Shibahara I, Saito R, Kanamori M, Kumabe T; et al. (2016). "Impact of gross total resection in patients with WHO grade III glioma harboring the IDH 1/2 mutation without the 1p/19q co-deletion". J Neurooncol. 129 (3): 505–514. doi:10.1007/s11060-016-2201-2. PMID 27401154.
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.
- ↑ Stark AM, Hugo HH, Mehdorn HM, Knerlich-Lukoschus F (2009). "Acute Hydrocephalus due to Secondary Leptomeningeal Dissemination of an Anaplastic Oligodendroglioma". Case Rep Med. 2009: 370901. doi:10.1155/2009/370901. PMC 2797365. PMID 20052406.