Nissl body

Jump to: navigation, search
Image of a Nissl-stained histological section through the rodent hippocampus showing various classes of neurons.
Motor nerve cell from ventral horn of medulla spinalis of rabbit. The angular and spindle-shaped Nissl bodies are well shown.

A Nissl body (or Nissl granule or tigroid body) is a large granular body found in neurons. It was named after Franz Nissl, German neurologist (1860-1919).

Nissl bodies can be demonstrated by a method of selective staining developed by Nissl (Nissl staining), using an aniline stain to label extranuclear RNA granules. RNA stains blue with this method due to its basophilic (lat. "base-loving") properties.

These granules are rough endoplasmic reticulum (with ribosomes) and are the site of protein synthesis.

Nissl bodies show changes under various physiological conditions and in pathological conditions they may dissolve and disappear (karyolysis).

See also

External links

de:Nissl-Färbunggl:Corpos de Nissl

Navigation WikiDoc | WikiPatient | Up To Date Pages | Recently Edited Pages | Recently Added Pictures

Table of Contents In Alphabetical Order | By Individual Diseases | Signs and Symptoms | Physical Examination | Lab Tests | Drugs

Editor Tools Become an Editor | Editors Help Menu | Create a Page | Edit a Page | Upload a Picture or File | Printable version | Permanent link | Maintain Pages | What Pages Link Here
There is no pharmaceutical or device industry support for this site and we need your viewer supported Donations | Editorial Board | Governance | Licensing | Disclaimers | Avoid Plagiarism | Policies