Muscularis mucosae

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Muscularis mucosae
Section of duodenum of cat. X 60. (Muscularis mucosae labeled at right, third from the top.)
Gray's subject #245 1144
Dorlands/Elsevier m_22/12548158


The lamina muscularis mucosae (or "muscularis mucosa") is the thin layer of smooth muscle found in most parts of the gastrointestinal tract, located outside the lamina propria mucosae and separating it from the submucosa.

In the gastrointestinal tract, the term mucosa or "mucous membrane" refers to the combination of epithelium, lamina propria, and (where it occurs) muscularis mucosa.[1] The etymology suggests this since the Latin names translate to "the mucosa's own special layer" (lamina propria mucosae) and "muscular layer of the mucosa" (lamina muscularis mucosae).

The muscularis mucosa is composed of several thin layers of smooth muscle fibers oriented in different ways which keeps the mucosal surface and underlying glands in a constant state of gentle agitation to expel contents of glandular crypts and enhance contact between epithelium and the contents of the lumen.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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