Molecular pathology
Overview
Molecular pathology is an emerging discipline within pathology which is focused on the use of nucleic acid-based techniques such as DNA sequencing, fluorescent in-situ hybridization, reverse-transcriptase polymerase chain reaction, and nucleic acid microarrays for specialised studies of disease. Molecular pathology shares some aspects of practice with both anatomic and clinical pathology, and is sometimes considered a "crossover" discipline. Applications are found in studies of both hereditary and acquired disorders including genetic diseaes, malignant tumors, hematological diseases (leukemias and lymphomas), and infectious diseases. DNA testing is the most common method for identity testing with applications such as bone marrow engraftment monitoring, paternity testing, and forensic identification.
Pathology | |
|---|---|
| Principles of pathology | Disease - Infection - Ischemia - Inflammation - Wound healing - Neoplasia - Hemodynamics
Cell death: Necrosis (Liquefactive necrosis, Coagulative necrosis, Caseous necrosis) - Apoptosis - Pyknosis - Karyorrhexis - Karyolysis Cellular adaptation: Atrophy - Hypertrophy - Hyperplasia - Dysplasia - Metaplasia accumulations: pigment (Hemosiderin, Lipochrome/Lipofuscin, Melanin) - Steatosis |
| Anatomical pathology | Surgical pathology - Cytopathology - Autopsy - Molecular pathology - Forensic pathology - Dental pathology Gross examination - Histopathology - Immunohistochemistry - Electron microscopy - Immunofluorescence - Fluorescent in situ hybridization |
| Clinical pathology | Clinical chemistry - Hematopathology - Transfusion medicine - Medical microbiology - Diagnostic immunology - Immunopathology Enzyme assay - Mass spectrometry - Chromatography - Flow cytometry - Blood bank - Microbiological culture - Serology |
Table of Contents In Alphabetical Order | By Individual Diseases | Signs and Symptoms | Physical Examination | Lab Tests | Drugs
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