Melkersson-Rosenthal syndrome

Jump to: navigation, search

WikiDoc Resources for Melkersson-Rosenthal syndrome

Articles

Most recent articles on Melkersson-Rosenthal syndrome

Most cited articles on Melkersson-Rosenthal syndrome

Review articles on Melkersson-Rosenthal syndrome

Articles on Melkersson-Rosenthal syndrome in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Melkersson-Rosenthal syndrome

Images of Melkersson-Rosenthal syndrome

Photos of Melkersson-Rosenthal syndrome

Podcasts & MP3s on Melkersson-Rosenthal syndrome

Videos on Melkersson-Rosenthal syndrome

Evidence Based Medicine

Cochrane Collaboration on Melkersson-Rosenthal syndrome

Bandolier on Melkersson-Rosenthal syndrome

TRIP on Melkersson-Rosenthal syndrome

Clinical Trials

Ongoing Trials on Melkersson-Rosenthal syndrome at Clinical Trials.gov

Trial results on Melkersson-Rosenthal syndrome

Clinical Trials on Melkersson-Rosenthal syndrome at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Melkersson-Rosenthal syndrome

NICE Guidance on Melkersson-Rosenthal syndrome

NHS PRODIGY Guidance

FDA on Melkersson-Rosenthal syndrome

CDC on Melkersson-Rosenthal syndrome

Books

Books on Melkersson-Rosenthal syndrome

News

Melkersson-Rosenthal syndrome in the news

Be alerted to news on Melkersson-Rosenthal syndrome

News trends on Melkersson-Rosenthal syndrome

Commentary

Blogs on Melkersson-Rosenthal syndrome

Definitions

Definitions of Melkersson-Rosenthal syndrome

Patient Resources / Community

Patient resources on Melkersson-Rosenthal syndrome

Discussion groups on Melkersson-Rosenthal syndrome

Patient Handouts on Melkersson-Rosenthal syndrome

Directions to Hospitals Treating Melkersson-Rosenthal syndrome

Risk calculators and risk factors for Melkersson-Rosenthal syndrome

Healthcare Provider Resources

Symptoms of Melkersson-Rosenthal syndrome

Causes & Risk Factors for Melkersson-Rosenthal syndrome

Diagnostic studies for Melkersson-Rosenthal syndrome

Treatment of Melkersson-Rosenthal syndrome

Continuing Medical Education (CME)

CME Programs on Melkersson-Rosenthal syndrome

International

Melkersson-Rosenthal syndrome en Espanol

Melkersson-Rosenthal syndrome en Francais

Business

Melkersson-Rosenthal syndrome in the Marketplace

Patents on Melkersson-Rosenthal syndrome

Experimental / Informatics

List of terms related to Melkersson-Rosenthal syndrome

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2].

Overview

Melkersson-Rosenthal syndrome is a rare neurological disorder characterized by recurring facial paralysis, swelling of the face and lips (usually the upper lip), and the development of folds and furrows in the tongue. Onset is in childhood or early adolescence. After recurrent attacks (ranging from days to years in between), swelling may persist and increase, eventually becoming permanent. The lip may become hard, cracked, and fissured with a reddish-brown discoloration. The cause of Melkersson-Rosenthal syndrome is unknown, but there may be a genetic predisposition. It can be symptomatic of Crohn's disease or sarcoidosis.

Treatment

Treatment is symptomatic and may include medication therapies with nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids to reduce swelling, as well as antibiotics and immunosuppressants. Surgery may be recommended to relieve pressure on the facial nerves and to reduce swollen tissue, but its effectiveness has not been established. Massage and electrical stimulation may also be prescribed.

Prognosis

Melkersson-Rosenthal syndrome may recur intermittently after its first appearance. It can become a chronic disorder. Follow-up care should exclude the development of Crohn's disease or sarcoidosis.

Eponym

It is named for Ernst Melkersson and Curt Rosenthal.[1][2][3]

Physical examination

Gallery

Head

Oral cavity

References

  1. synd/9 at Who Named It
  2. E. Melkersson. Ett fall av recidiverande facialispares i samband med ett angioneurotiskt ødem. Hygiea, Stockholm, 1928, 90: 737-41.
  3. C. Rosenthal. Klinisch-erbbiologischer Beitrag zur Konstitutionspathologie. Gemeinsames Auftreten von Facialislähmung, angioneurotischem Gesichtsödem und Lingua plicata in Arthritismus-Familien. Zeitschrift für die gesamte Neurologie und Psychiatrie, 1931, 131: 475-501.

Source

The original version of this article was taken from the public domain source at http://www.ninds.nih.gov/disorders/melkersson/melkersson.htm


de:Melkersson-Rosenthal-Syndrom sv:Melkersson-Rosenthals syndrom



Linked-in.jpg