Mediastinitis
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| Mediastinitis Classification and external resources | |
| ICD-10 | J98.5 |
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| ICD-9 | 519.2 |
| DiseasesDB | 7909 |
| MedlinePlus | 000081 |
| eMedicine | med/2798 |
| MeSH | D008480 |
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WikiDoc Resources for Mediastinitis | |
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Most recent articles on Mediastinitis Most cited articles on Mediastinitis | |
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Ongoing Trials on Mediastinitis at Clinical Trials.gov Trial results on Mediastinitis Clinical Trials on Mediastinitis at Google
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US National Guidelines Clearinghouse on Mediastinitis NICE Guidance on Mediastinitis
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Patient resources on Mediastinitis Discussion groups on Mediastinitis Patient Handouts on Mediastinitis Directions to Hospitals Treating Mediastinitis Risk calculators and risk factors for Mediastinitis
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Causes & Risk Factors for Mediastinitis | |
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Overview
Mediastinitis is inflammation of the tissues in the mid-chest, or mediastinum. It can be either acute or chronic.
Acute mediastinitis is usually bacterial and due to rupture of organs in the mediastinum. As the infection can progress rapidly, this is considered a serious condition. Chronic sclerosing (or fibrosing) mediastinitis, while potentially serious, is caused by a long-standing inflammation of the mediastinum, leading to growth of acellular collagen and fibrous tissue within the chest and around the central vessels and airways. It has a different cause, treatment, and prognosis than acute infectious mediastinitis.
Causes and treatment
Acute
Before the development of modern cardiovascular surgery, cases of acute mediastinitis usually arose from either perforation of the esophagus or from contiguous spread of odontogenic or retropharyngeal infections. However, in modern practice, most cases of acute mediastinitis result from complications of cardiovascular or endoscopic surgical procedures.
Treatment usually involves aggressive intravenous antibiotic therapy and hydration. If discrete fluid collections (such as abscesses) have formed, they may have to be surgically drained.
Chronic
Chronic medistinitis is usually a radiologic diagnosis manifested by diffuse fibrosis of the soft tissues of the mediastinum. This is sometimes the consequence of prior granulomatous disease, most commonly histoplasmosis. Other identifiable causes include tuberculosis and radiation therapy. Fibrosing mediastinitis most frequently causes problems by constricting blood vessels or airways in the mediastinum. This may result in such complications as superior vena cava syndrome or pulmonary edema from compression of pulmonary veins.
Treatment for chronic fibrosing mediastinitis is somewhat controversial, and may include steroids or surgical decompression of affected vessels.
External links
- -6684651 at GPnotebook
- MeSH Mediastinitis
- Fibrosing Mediastinitis
- Fibrosing Mediastinitis Jason's Site
- Tami Jo's Site on FM
- Mediastinal Germ Cell Tumors
WikiDoc Research Resources for Mediastinitis | |
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| Articles on Mediastinitis | Most recent articles on Mediastinitis • Most cited articles on Mediastinitis • Review articles on Mediastinitis • Articles on Mediastinitis in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on Mediastinitis | Powerpoint slides on Mediastinitis • Images of Mediastinitis • Photos of Mediastinitis • Podcasts & MP3s on Mediastinitis • Videos on Mediastinitis |
| Evidence Based Medicine Regarding Mediastinitis | Cochrane Collaboration on Mediastinitis • Bandolier on Mediastinitis • TRIP on Mediastinitis |
| Cost Effectiveness of Mediastinitis | Cost Effectiveness of Mediastinitis |
| Clinical Trials Involving Mediastinitis | Ongoing Trials on Mediastinitis at Clinical Trials.gov • Trial results on Mediastinitis • Clinical Trials on Mediastinitis at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding Mediastinitis | US National Guidelines Clearinghouse on Mediastinitis • NICE Guidance on Mediastinitis • NHS PRODIGY Guidance • FDA on Mediastinitis • CDC on Mediastinitis |
| Textbook Information on Mediastinitis | Books and Textbook Information on Mediastinitis |
| Pharmacology Resources on Mediastinitis | Dosing of Mediastinitis • Drug interactions with Mediastinitis • Side effects of Mediastinitis • Allergic reactions to Mediastinitis • Overdose information on Mediastinitis • Carcinogenicity information on Mediastinitis • Mediastinitis in pregnancy • Pharmacokinetics of Mediastinitis • |
| Genetics, Pharmacogenomics, and Proteinomics of Mediastinitis | Genetics of Mediastinitis • Pharmacogenomics of Mediastinitis • Proteomics of Mediastinitis |
| Newstories on Mediastinitis | Mediastinitis in the news • Be alerted to news on Mediastinitis • News trends on Mediastinitis |
| Commentary on Mediastinitis | Blogs on Mediastinitis |
| Patient Resources on Mediastinitis | Patient resources on Mediastinitis • Discussion groups on Mediastinitis • Patient Handouts on Mediastinitis • Directions to Hospitals Treating Mediastinitis • Risk calculators and risk factors for Mediastinitis |
| Healthcare Provider Resources on Mediastinitis | Symptoms of Mediastinitis • Causes & Risk Factors for Mediastinitis • Diagnostic studies for Mediastinitis • Treatment of Mediastinitis |
| Continuing Medical Education (CME) Programs on Mediastinitis | CME Programs on Mediastinitis |
| International Resources on Mediastinitis | Mediastinitis en Espanol • Mediastinitis en Francais |
| Business Resources on Mediastinitis | Mediastinitis in the Marketplace • Patents on Mediastinitis |
| Informatics Resources on Mediastinitis | List of terms related to Mediastinitis |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
