Median aperture

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Brain: Median aperture
Scheme of roof of fourth ventricle. The arrow is in the foramen of Majendie.
Latin apertura mediana ventriculi quarti
Gray's subject #187 798
NeuroNames hier-638
Dorlands/Elsevier a_51/12144687

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


The median aperture of the brain (or foramen of Magendie) is an opening in the hollow nerve tube, connecting the fourth ventricle of the brain with the subarachnoid space.

The median aperture, along with the two lateral apertures (foramina of Luschka), one on the left and one on the right, are the three primary routes for cerebrospinal fluid to escape into the cisterna magna.


The Foramen of Magendie is named for François Magendie, who first described it.[1]


  • Netter, Frank H. (1989) Atlas of Human Anatomy. Summit, NJ: Ciba-Geigy Corporation.
  • Williams, Peter L.; Warwick, Roger; Dyson, Mary; & Bannister, Lawrence H. (1989) Gray's Anatomy (37th ed.). New York: Churchill Livingstone.

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