McN5652

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McN5652 is a molecule that can be radiolabeled and then used as a radioligand in positron emission tomography (PET) studies. The [11C](+)McN5652 enantiomer binds to the serotonin transporter.[1]

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The radioligand is used for molecular neuroimaging, but also for imaging of the lungs.[2]

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References

  1. M. Suehiro, U. Scheffel, H. T. Ravert, R. F. Dannals & H. N. Jr Wagner (1993). "[11C](+)McN5652 as a radiotracer for imaging serotonin uptake sites with PET". Life Sciences. 53 (11): 883–882. doi:10.1016/0024-3205(93)90440-E. PMID 8366755.
  2. Akihiro Takano, Hiroshi Ito, Yasuhiko Sudo, Makoto Inoue, Tetsuya Ichimiya, Fumihiko Yasuno, Kazutoshi Suzuki & Tetsuya Suhara (2007). "Effects of smoking on the lung accumulation of [11C]McN5652". Annals of Nuclear Medicine. 21 (6): 349–344. doi:10.1007/s12149-007-0031-1. PMID 17705015. Unknown parameter |month= ignored (help)


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