Linear IgA bullous dermatosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Synonyms and keywords:

Overview

Linear IgA bullous dermatosis (also known as "Linear IgA dermatosis") is frequently associated with medication exposure, especially vancomycin, with men and women being equally affected.^[1]^:135 It was first described by Tadeusz Chorzelski in 1979. Linear IgA dermatosis is a rare immune-mediated blistering skin disease that may be divided into two types:^[2]^:587

Adult linear IgA disease is an acquired, autoimmune blistering disease that may present with a clinical pattern of vesicles indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullous pemphigoid-like appearance. ^[1]
Childhood linear IgA disease (also known as "Chronic bullous disease of childhood") is an acquired, self-limited bullous disease that may begin by the time the patient is age 2 to 3 and usually remits by age 13. ^[1]

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Linear IgA bullous dermatosis from other Diseases

Epidemiology and Demographics

Age

Gender

Race

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

Symptoms

Physical Examination

Skin

Trunk And Extremities

Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

References

↑ ^1.0 ^1.1 ^1.2 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
↑ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
↑ ^3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 "Dermatology Atlas".

Template:Vesiculobullous disease

[Andrews-1] 1.0 ^1.1 ^1.2 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.

[Fitz2-2] Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.

[Dermatology_Atlas-3] 3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 "Dermatology Atlas".

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