Levothyroxine
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Synonyms / Brand Names: (-)-Thyroxine, 3,3',5,5'-Tetraiodo-L-thyronine, L-Thryoxin, L-Thyroxine, Laevothyroxinum, Levo-t, Levothyroxine Sodium, Tetraiodothyronine, THX, Thyroxine iodine, Levothyroxin, T4 levothyroxine, O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine, Eltroxin, Euthyrox, Laevoxin, Letter, Levaxin, Levolet, Levothroid, Levothyrox, Levoxine, Levoxyl, Novothyrox, Oroxine, Synthroid, Synthroid Sodium, Thyratabs, Thyrax, Thyreoideum, Thyro-tabs, Thyroxevan, Thyroxin, Thyroxinal, Unithroid
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753
Dosing and Administration
In patients with severe hypothyroidism, the recommended initial Levothyroxine sodium dose is 12.5 to 25 mcg/day with increases of 25 mcg/day every 2 to 4 weeks, accompanied by clinical and laboratory assessment, until the TSH level is normalized.
Levothyroxine sodium tablets should be taken in the morning on an empty stomach, at least one-half hour before any food is eaten. Levothyroxine sodium tablets should be taken at least 4 hours apart from drugs that are known to interfere with its absorption.
FDA Package Insert Resources
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FDA Package Insert Resources
Indications
Contraindications
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FDA label
FDA on Levothyroxine
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Publication Resources
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Review Articles on Levothyroxine
Articles on Levothyroxine in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Levothyroxine
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Trial Resources
Ongoing Trials with Levothyroxine at Clinical Trials.gov
Trial Results with Levothyroxine
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Levothyroxine
Cochrane Collaboration on Levothyroxine
Cost Effectiveness of Levothyroxine
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Patient Resources
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Patient Resources on Levothyroxine
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Levothyroxine en Español
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The content of this page is taken from the FDA package insert for this drug and should not be edited.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
