Langhans giant cell

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Overview

Langhans giant cells are large cells found in granulomatous conditions. They are formed by the fusion of epithelioid cells (macrophages), and contain nuclei arranged in a horseshoe-shaped pattern in the cell periphery. Their presence could indicate tuberculosis.

They should not be confused with Langerhans cell. According to MeSH, Langhans giant cells are macrophages, but Langerhans cells are not. "Langerhans" may also refer to the Islets of Langerhans that are found in the pancreas.

Langhans giant cells are named for Theodor Langhans (1839-1915), a German pathologist ^[1]

References

• http://de.wikipedia.org/wiki/Theodor_Langhans (link to German Wikipedia)

External links

• MeSH Langhans+giant+cells
• Histology at ohio-state.edu
• Histology at jhu.edu

v • d • e Blood
General	Plasma – Hematopoietic stem cells
Lymphoid – WBC	T cells: Cytotoxic CD8+, Helper CD4+/Regulatory, γδ, Natural Killer T cell B cells: Plasma, Memory Natural killer cells (Lymphokine-activated killer cell) Null cell
Myeloid – WBC	Monocytes/Macrophages (Histiocytes, Kupffer cells, Dust cell, Microglia, Osteoclasts, Epithelioid cells, Langhans giant cells, Foreign-body giant cell) Granulocytes (Neutrophil, Eosinophil, Basophil) – Mast cell precursors Dendritic cells (Langerhans cells, Follicular dendritic cells) Megakaryoblast – Megakaryocyte – Platelets
Myeloid – RBC	Reticulocyte – Normoblast

v • d • e WikiDoc Research Resources for Langhans giant cell
Articles on Langhans giant cell	Most recent articles on Langhans giant cell • Most cited articles on Langhans giant cell • Review articles on Langhans giant cell • Articles on Langhans giant cell in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Langhans giant cell	Powerpoint slides on Langhans giant cell • Images of Langhans giant cell • Photos of Langhans giant cell • Podcasts & MP3s on Langhans giant cell • Videos on Langhans giant cell
Evidence Based Medicine Regarding Langhans giant cell	Cochrane Collaboration on Langhans giant cell • Bandolier on Langhans giant cell • TRIP on Langhans giant cell
Cost Effectiveness of Langhans giant cell	Cost Effectiveness of Langhans giant cell
Clinical Trials Involving Langhans giant cell	Ongoing Trials on Langhans giant cell at Clinical Trials.gov • Trial results on Langhans giant cell • Clinical Trials on Langhans giant cell at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Langhans giant cell	US National Guidelines Clearinghouse on Langhans giant cell • NICE Guidance on Langhans giant cell • NHS PRODIGY Guidance • FDA on Langhans giant cell • CDC on Langhans giant cell
Textbook Information on Langhans giant cell	Books and Textbook Information on Langhans giant cell
Pharmacology Resources on Langhans giant cell	Dosing of Langhans giant cell • Drug interactions with Langhans giant cell • Side effects of Langhans giant cell • Allergic reactions to Langhans giant cell • Overdose information on Langhans giant cell • Carcinogenicity information on Langhans giant cell • Langhans giant cell in pregnancy • Pharmacokinetics of Langhans giant cell •
Genetics, Pharmacogenomics, and Proteinomics of Langhans giant cell	Genetics of Langhans giant cell • Pharmacogenomics of Langhans giant cell • Proteomics of Langhans giant cell
Newstories on Langhans giant cell	Langhans giant cell in the news • Be alerted to news on Langhans giant cell • News trends on Langhans giant cell
Commentary on Langhans giant cell	Blogs on Langhans giant cell
Patient Resources on Langhans giant cell	Patient resources on Langhans giant cell • Discussion groups on Langhans giant cell • Patient Handouts on Langhans giant cell • Directions to Hospitals Treating Langhans giant cell • Risk calculators and risk factors for Langhans giant cell
Healthcare Provider Resources on Langhans giant cell	Symptoms of Langhans giant cell • Causes & Risk Factors for Langhans giant cell • Diagnostic studies for Langhans giant cell • Treatment of Langhans giant cell
Continuing Medical Education (CME) Programs on Langhans giant cell	CME Programs on Langhans giant cell
International Resources on Langhans giant cell	Langhans giant cell en Espanol • Langhans giant cell en Francais
Business Resources on Langhans giant cell	Langhans giant cell in the Marketplace • Patents on Langhans giant cell
Informatics Resources on Langhans giant cell	List of terms related to Langhans giant cell