Kasabach-Merritt syndrome laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The diagnostic workup is directed by the presenting signs and symptoms, and can involve:

• blood counts, clotting studies, and other laboratory testing
• imaging tests (ultrasound, CT scan, MRI, sometimes angiography, and rarely nuclear medicine scans)
• biopsy of the tumor.

Laboratory Findings

Patients uniformly show severe thrombocytopenia, low fibrinogen levels, high fibrin degradation products (due to fibrinolysis), and microangiopathic hemolysis.