Jeryl Lynn
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Jeryl Lynn are strains of mumps virus used in the Mumpsvax mumps vaccine made by Merck. The strains are named after Jeryl Lynn Hilleman. In 1963 Ms. Hilleman's father Dr. Maurice Hilleman, was leading efforts to produce a mumps vaccine for Merck. He cultured the Mumps virus from her throat, and in 1967 a vaccine was produced from this which is now widely used.[1]
The Jeryl Lynn strains used in the manufacture of Mumpsvax later turned out to contain two distinguishable viral substrains, JL1 and JL2.[1] Further research showed that the JL1 strain was preferentially selected by propagation in Vero and CEF cell cultures. The JL2 strain was preferentially selected by passage in embryonated chicken eggs.[1]
In the U.S.A. the Jeryl Lynn strain-based vaccines supplanted the previous, killed virus, vaccine in 1978.[1]
References
See also
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| See also | List of vaccine topics • Epidemiology |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
