Jan Evangelista Purkyně

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Jan Evangelista Purkyně (also written Johannes Evangelists Purkinje, listen ) (17th December,1787 - 28th July, 1869) was a Czech anatomist, patriot, and physiologist.

Purkyně was born in Libochovice, Bohemia. In 1819 he graduated from the University of Prague with a degree in medicine, where he was appointed a Professor of Physiology after writing his doctoral dissertation. Working at the university, he discovered the Purkinje effect, whereby as light intensity decreases red objects seem to fade faster than blue objects of the same brightness. He published two volumes Observations and Experiments Investigating the Physiology of Senses and New Subjective Reports about Vision, which contributed to the emergence of the science of experimental psychology. He created the world's first Department of Physiology at the University of Breslau in Prussia in 1839 and the world's first official physiology laboratory in 1842.

He is best known for his 1837 discovery of Purkinje cells, large neurons with many branching dendrites found in the cerebellum. He is also known for his discovery, in 1839 of Purkinje fibres, the fibrous tissue that conducts electrical impulses from the atrioventricular node to all parts of the ventricles of the heart. Other discoveries include Purkinje images, reflections of objects from structures of the eye, and the Purkinje shift, the change in the brightness of red and blue colours as light intensity decreases gradually at dusk. Purkinje also introduced the scientific terms plasma (for the component of blood left when the suspended cells have been removed) and protoplasm (the substance found inside cells).

Purkinje was the first to use a microtome to make wafer thin slices of tissue for microscopic examination and was among the first to use an improved version of the compound microscope. He described the effects of camphor, opium, belladonna and turpentine on humans in 1829, discovered sweat glands in 1833 and recognised fingerprints as a method of indentification in 1823.

He is buried in the Czech National Cemetery in Vyšehrad, Prague, Czech Republic.

Legacy

The Masaryk University in Brno, Czech Republic, bore his name from 1960 to 1990, as did the standalone military medical academy in Hradec Kralové (1994 - 2004). Today a university in Ústí nad Labem bears his name: Jan Evangelista Purkyně University in Ustí nad Labem (Univerzita Jana Evangelisty Purkyně v Ústí nad Labem).

Purkyně crater on the Moon is named after him, as is the asteroid 3701 Purkyně.

References

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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