J chain
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1: Base unit.
2: Heavy chains.
3: Light chains.
4: J chain.
5: Intermolecular disulfide bonds.
J chain is a protein component of the antibodies IgM and IgA.
Because IgM and IgA are the only two types of antibody that polymerize, it was initially thought that J chain was required for polymerization. However, it was subsequently found that IgM is able to polymerize in the absence of J chain as both a pentamer and a hexamer.
It is now believed that J chain is necessary to enable secretion of antibodies into mucosal tissues.
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