Iodine-125

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Iodine-125 is a radioisotope of iodine which has uses in biological assays and in radiation therapy to treat prostate cancer and brain tumors. Its half-life is around 60 days and it emits gamma-rays with maximum energies of 35 keV, some of which are internally converted to x-rays. Iodine-125 is created by the electron capture decay of Xenon-125, which is a synthetic isotope of Xenon, itself created by neutron capture of the slightly radioactive Xenon-124, which occurs naturally with an abundance of around 0.1%. Because of the synthetic production route of Iodine-125 and its short half-life, the natural abundance is effectively 0%.

Physical Data

  • Element: Iodine
  • Z: 54
  • A: 125
  • Atomic Mass:
  • Density:
  • Physical state: Solid at room temperature
  • Isotopic abundance: 0%


  • Radioactive: Yes
  • T(1/2): 59.4 days
  • Decay: Electron capture to Tellurium-125
  • Emissions: Gamma-rays at 35.5 keV. 7% emitted, 93% internally converted to:
    • 27.0 keV (113% abundance relative to 7% gamm emission)
    • 31.0 keV (26%)
    • 27-32 keV (14%)
  • Half-value layer: 0.025 mm Pb

References

  • Harper, P.V. ; Siemens, W.D. ; Lathrop, K.A. ; Brizel, H.E. ; Harrison, R.W. Iodine-125. Proc. Japan Conf. Radioisotopes; Vol: 4th Jan 01, 1961
  • ORCBS

Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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