Impaired glucose tolerance

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Evidence Based Medicine
Cochrane Collaboration on Impaired glucose tolerance Bandolier on Impaired glucose tolerance TRIP on Impaired glucose tolerance
Clinical Trials
Ongoing Trials on Impaired glucose tolerance at Clinical Trials.gov Trial results on Impaired glucose tolerance Clinical Trials on Impaired glucose tolerance at Google
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Overview

Impaired Glucose Tolerance (IGT) is a pre-diabetic state of dysglycemia, that is associated with insulin resistance and increased risk of cardiovascular pathology. IGT may precede type 2 diabetes mellitus by many years. IGT is also a risk factor for mortality.

Criteria

Diabetes mellitus
Types of Diabetes
Diabetes mellitus type 1 Diabetes mellitus type 2 Gestational diabetes Pre-diabetes: Impaired fasting glycaemia Impaired glucose tolerance
Disease Management
Diabetes management: •Diabetic diet •Anti-diabetic drugs •Conventional insulinotherapy •Intensive insulinotherapy
Other Concerns
Cardiovascular disease Diabetic comas: •Diabetic hypoglycemia •Diabetic ketoacidosis •Nonketotic hyperosmolar Diabetic myonecrosis Diabetic nephropathy Diabetic neuropathy Diabetic retinopathy Diabetes and pregnancy
Blood tests
Blood sugar Fructosamine Glucose tolerance test Glycosylated hemoglobin

According to the criteria of the World Health Organization and the American Diabetes Association, impaired glucose tolerance is defined as:

• two-hour glucose levels of 140 to 199 mg per dL (7.8 to 11.0 mmol) on the 75-g oral glucose tolerance test. A patient is said to be under the condition of IGT when he/she has an intermediately raised glucose level after 2 hours, but less than would qualify for type 2 diabetes mellitus. The fasting glucose may be either normal or mildly elevated.

From 10 to 15 percent of adults in the United States have one of these conditions.

Treatment

The risk of progression to diabetes and development of cardiovascular disease is greater than for Impaired fasting glycaemia.

Although some drugs can delay the onset of diabetes, lifestyle modifications play a greater role in the prevention of the disease. Patients identified as having an IGT should exercise regularly and have a balanced diet removing the empty calories of sugar.

Carnitine has been shown to improve glucose uptake, regulation, and oxidation, though temporarily (i.e. only when levels are sustained in the blood).

References

See also

• Impaired fasting glycaemia
• Glucose tolerance test

Acknowledgements

The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.

Initial content for this page in some instances came from Wikipedia

List of contributors:

Suggested Reading and Key General References

Suggested Links and Web Resources

For Patients

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v • d • e WikiDoc Research Resources for Impaired glucose tolerance (Click show to right to view)
Articles on Impaired glucose tolerance	Most recent articles on Impaired glucose tolerance • Most cited articles on Impaired glucose tolerance • Review articles on Impaired glucose tolerance • Articles on Impaired glucose tolerance in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Impaired glucose tolerance	Powerpoint slides on Impaired glucose tolerance • Images of Impaired glucose tolerance • Photos of Impaired glucose tolerance • Podcasts & MP3s on Impaired glucose tolerance • Videos on Impaired glucose tolerance
Evidence Based Medicine Regarding Impaired glucose tolerance	Cochrane Collaboration on Impaired glucose tolerance • Bandolier on Impaired glucose tolerance • TRIP on Impaired glucose tolerance
Cost Effectiveness of Impaired glucose tolerance	Cost Effectiveness of Impaired glucose tolerance
Clinical Trials Involving Impaired glucose tolerance	Ongoing Trials on Impaired glucose tolerance at Clinical Trials.gov • Trial results on Impaired glucose tolerance • Clinical Trials on Impaired glucose tolerance at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Impaired glucose tolerance	US National Guidelines Clearinghouse on Impaired glucose tolerance • NICE Guidance on Impaired glucose tolerance • NHS PRODIGY Guidance • FDA on Impaired glucose tolerance • CDC on Impaired glucose tolerance
Textbook Information on Impaired glucose tolerance	Books and Textbook Information on Impaired glucose tolerance
Pharmacology Resources on Impaired glucose tolerance	Dosing of Impaired glucose tolerance • Drug interactions with Impaired glucose tolerance • Side effects of Impaired glucose tolerance • Allergic reactions to Impaired glucose tolerance • Overdose information on Impaired glucose tolerance • Carcinogenicity information on Impaired glucose tolerance • Impaired glucose tolerance in pregnancy • Pharmacokinetics of Impaired glucose tolerance •
Genetics, Pharmacogenomics, and Proteinomics of Impaired glucose tolerance	Genetics of Impaired glucose tolerance • Pharmacogenomics of Impaired glucose tolerance • Proteomics of Impaired glucose tolerance
Newstories on Impaired glucose tolerance	Impaired glucose tolerance in the news • Be alerted to news on Impaired glucose tolerance • News trends on Impaired glucose tolerance
Commentary on Impaired glucose tolerance	Blogs on Impaired glucose tolerance
Patient Resources on Impaired glucose tolerance	Patient resources on Impaired glucose tolerance • Discussion groups on Impaired glucose tolerance • Patient Handouts on Impaired glucose tolerance • Directions to Hospitals Treating Impaired glucose tolerance • Risk calculators and risk factors for Impaired glucose tolerance
Healthcare Provider Resources on Impaired glucose tolerance	Symptoms of Impaired glucose tolerance • Causes & Risk Factors for Impaired glucose tolerance • Diagnostic studies for Impaired glucose tolerance • Treatment of Impaired glucose tolerance
Continuing Medical Education (CME) Programs on Impaired glucose tolerance	CME Programs on Impaired glucose tolerance
International Resources on Impaired glucose tolerance	Impaired glucose tolerance en Espanol • Impaired glucose tolerance en Francais
Business Resources on Impaired glucose tolerance	Impaired glucose tolerance in the Marketplace • Patents on Impaired glucose tolerance
Informatics Resources on Impaired glucose tolerance	List of terms related to Impaired glucose tolerance

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .