High endothelial venules

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]



High endothelial venules, or HEVs, are a subtype of blood endothelium present within lymph nodes; used by various leukocytes to gain entry into the lymph node via the blood.[1]

The HEVs are made up of cuboidal endothelial cells, with various receptors to allow entry/rolling interactions between leukocytes and the endothelium.

High endothelial venules are found in lymph nodes and tonsils and Peyer's patches, but not in the thymus or spleen.[2]

References

  1. UIUC Histology Subject 565
  2. http://www.bu.edu/histology/m/schema03.htm#chart1

de:High endothelial venule


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