Glypican 6

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	Wikidata
View/Edit Human

Glypican-6 is a protein that in humans is encoded by the GPC6 gene.^[1]^[2]

The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans. The glypicans have been implicated in the control of cell growth and division. Glypican 6 is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases.^[2]

References

↑ Paine-Saunders S, Viviano BL, Saunders S (Aug 1999). "GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC4 and is colocalized with GPC5 on human chromosome 13". Genomics. 57 (3): 455–8. doi:10.1006/geno.1999.5793. PMID 10329016.
↑ ^2.0 ^2.1 "Entrez Gene: GPC6 glypican 6".

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Veugelers M, De Cat B, Ceulemans H, et al. (1999). "Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans". J. Biol. Chem. 274 (38): 26968–77. doi:10.1074/jbc.274.38.26968. PMID 10480909.
Watanabe K, Yamada H, Yamaguchi Y (1995). "K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney". J. Cell Biol. 130 (5): 1207–18. doi:10.1083/jcb.130.5.1207. PMC 2120559. PMID 7657705.

External links

GPC6 human gene location in the UCSC Genome Browser.
GPC6 human gene details in the UCSC Genome Browser.

This article on a gene on human chromosome 13 is a stub. You can help Wikipedia by expanding it.

[pmid10329016-1] Paine-Saunders S, Viviano BL, Saunders S (Aug 1999). "GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC4 and is colocalized with GPC5 on human chromosome 13". Genomics. 57 (3): 455–8. doi:10.1006/geno.1999.5793. PMID 10329016.

[entrez-2] 2.0 ^2.1 "Entrez Gene: GPC6 glypican 6".

[1]

[2]

Glypican 6

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References

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