Germ cell tumor historical perspective

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  • Polyebryoma was first described in 1936 by the French investigator Felix Albert Peyron who had a remarkable interest in polyembryoma neoplasm. He started his research paper in 1919 and wrote his last paper in 1941. His first work involves testicular polyembryoma. It can also be seen in the ovary [1]
  • In 2007, Looijenga and colleagues reviewed studies of GCT risk in various DSD diagnoses known at that time, and developed risk categories based on the consensus nomenclature, which have been incrementally refined since that time [2]



References

  1. Young RH, Stall JN, Sevestre H (2016). "The Polyembryoma: One of the Most Intriguing Human Neoplasms, With Comments on the Investigator Who Brought it to Light, Albert Peyron". Int J Gynecol Pathol. 35 (2): 93–105. doi:10.1097/PGP.0000000000000282. PMID 26840034.
  2. Looijenga LH, Hersmus R, Oosterhuis JW, Cools M, Drop SL, Wolffenbuttel KP (2007). "Tumor risk in disorders of sex development (DSD)". Best Pract Res Clin Endocrinol Metab. 21 (3): 480–95. doi:10.1016/j.beem.2007.05.001. PMID 17875493.