Follicular dendritic cells

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Follicular dendritic cells (FDC) are cells of the immune system found in lymph follicles. They are probably not of hematopoietic origin, but simply look similar to true dendritic cells. They share their appearance and function with the other types of dendritic cells. They are, however, classified differently in MeSH.

They assist in B cell maturation by the presentation of intact antigen to the B cells. This occurs in the germinal centers of peripheral lymphoid organs and induces class switching and proliferation.