Fluorometholone

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Fluorometholone
Systematic (IUPAC) name
(6S,8S,9R,10S,11S,13S,14S,17R)- 17-acetyl-9-fluoro-11,17-dihydroxy- 6,10,13-trimethyl- 6,7,8,11,12,14,15,16- octahydrocyclopenta[a] phenanthren-3-one
Identifiers
CAS number	426-13-1
ATC code	C05AA06 D07 AB06, D07 XB04, D10 AA01, S01 BA07, S01 CB05
PubChem	9878
DrugBank	APRD00980
Chemical data
Formula	C₂₂H₂₉F O₄
Mol. mass	376.462 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	C
Legal status
Routes	?

File:Flucon.JPG

Flucon as perscribed in Australia.

Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon).

FLUOROMETHOLONE ACETATE OPHTHALMIC Suspension is indicated for use in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.

External links

v • d • e

Corticosteroids - glucocorticoid/receptor and mineralocorticoid/receptor
(A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B)

Endogenous

Aldosterone, Cortisone, Hydrocortisone/cortisol, Desoxycortone

Others

Alclometasone, Amcinonide, Beclometasone, Betamethasone, Budesonide, Ciclesonide, Clobetasol, Clobetasone, Clocortolone, Cloprednol, Cortivazol, Deflazacort, Deoxycorticosterone, Desonide, Desoximetasone, Dexamethasone, Diflorasone, Diflucortolone, Difluprednate, Fluclorolone, Fludrocortisone, Fludroxycortide, Flumetasone, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortin, Fluocortolone, Fluorometholone, Fluperolone, Fluprednidene, Fluticasone, Formocortal, Halcinonide, Halometasone, Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate, Loteprednol, Medrysone, Meprednisone, Methylprednisolone,Methylprednisolone aceponate, Mometasone furoate, Paramethasone, Prednicarbate, Prednisone, Prednisolone, Prednylidene, Rimexolone, Tixocortol, Triamcinolone, Ulobetasol

v • d • e Vasoprotectives (C05)
Antihemorrhoidals for topical use	corticosteroids (Hydrocortisone, Prednisolone, Betamethasone, Fluorometholone, Fluocortolone, Dexamethasone, Fluocinolone acetonide, Fluocinonide) - local anesthetics (Lidocaine, Tetracaine, Benzocaine, Cinchocaine, Procaine, Oxetacaine, Pramocaine) - other (Tribenoside)
Antivaricose therapy	heparins or heparinoids for topical use (Organo-heparinoid, Sodium apolate, Heparin, Pentosan polysulfate) - sclerosing agents for local injection (Monoethanolamine oleate, Polidocanol, Invert sugar, Sodium tetradecyl sulfate, Phenol) - Other (Calcium dobesilate)
Capillary stabilising agents	bioflavonoids (Rutoside, Monoxerutin, Diosmin, Troxerutin, Hidrosmin) - other (Tribenoside)