Extraglomerular mesangial cell

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Overview

Extraglomerular mesangial cells (or lacis cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.

Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the thick ascending limb of Henle and Juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood. Although is it has been associated with the secretion of EPO. [1]

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References

  1. Junqueira, Luiz C.; Jose Carneiro (2003). Basic Histology. McGraw-Hill. ISBN 0838505902.  Cite uses deprecated parameter |coauthors= (help)

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