Diatrizoic acid
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| Diatrizoic acid | |
|---|---|
| Image:DiatrizoicAcid.PNG | |
| IUPAC name | 3,5-diacetamido-2,4,6-triiodo-benzoic acid |
| Identifiers | |
| CAS number | |
| SMILES | CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)NC(=O)C)I |
| Properties | |
| Molecular formula | C11H9I3N2O4 |
| Molar mass | 613.9 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
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Diatrizoic acid (or its anionic form, Diatrizoate), also known as amidotrizoic acid, or 3,5-Diacetamido-2,4,6-triiodobenzoic acid, is an iodine-containing radiocontrast agent. It is also used to kill tapeworms.
Diatrizoate is considered a high-osmolality contrast agent. Its osmolality ranges from approximately 1500 mOsm/kg (50% solution)[1] to over 2000 mOsm/kg (76% solution).[1]
Administration
- It is given intravenously (under brand name Hypaque®, GE Healthcare) to enhance contrast in computed tomography, to image the kidneys and related structures, and to image blood vessels.
- It is given orally or by enema (Gastrografin®, Gastrovist®, Gastrovision®, MD-Gastroview®) to image the gastrointestinal tract.
- It is given by Foley catheter (Cystografin®) to image the urinary tract
Contraindications
A history of sensitivity to iodine is not a contraindication to using diatrizoate, although it suggests caution in use of the agent.
References
de:Amidotrizoesäure fr:Acide diatrizoïque
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
