Daidzein
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| Daidzein | |
|---|---|
| Image:Daidzein.png | |
| IUPAC name | 7-Hydroxy-3-(4-hydroxyphenyl)chromen-4-one |
| Other names | 4',7-Dihydroxyisoflavone Daidzeol Isoaurostatin |
| Identifiers | |
| CAS number | |
| PubChem | |
| SMILES | C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O |
| Properties | |
| Molecular formula | C15H10O4 |
| Molar mass | 254.237 g/mol |
| Appearance | Pale yellow prisms |
| Melting point |
315-323 °C (decomposes) |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
Daidzein is one of several known isoflavones. Isoflavones compounds, such as daidzein and genistein, are found in a number of plants, but soybeans and soy products like tofu and textured vegetable protein are the primary food source. Soy isoflavones are a group of compounds found in and isolated from the soybean. Besides functioning as antioxidants, many isoflavones have been shown to interact with animal and human estrogen receptors, and are therefore known as phytoestrogens. Soy isoflavones also produce non-hormonal effects.
Isoflavones act as antioxidants to counteract damaging effects of free radicals in tissues. Isoflavones can act like estrogen in stimulating development and maintenance of female characteristics or they can block cells from using other forms of estrogen[citation needed]. Isoflavones also have been found to have antiangiogenic effects (blocking formation of new blood vessels)[citation needed], and may block the uncontrolled cell growth associated with cancer, most likely by inhibiting the activity of substances in the body that regulate cell division and cell survival (growth factors)[citation needed].
Studies show that groups of people who eat large amounts of soy-based products have lower incidences of breast, colon, endometrial, and prostate cancers than the general (US) population[citation needed]. Initial studies of soy isoflavone mixtures containing genistein, daidzein, and glycitein have found them safe for human use[1]. Laboratory studies using animals models have shown that both soy and isoflavones can be protective against cancer when given during early life but can stimulate response to cancer-causing chemicals when given during fetal development or when circulating levels of estrogen are low (menopause)[citation needed].
References
- ↑ Safety of soy-based infant formulas containing isoflavones PMID 15113975
External links
de:DaidzeinAcknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
