D-4-hydroxyphenylglycine transaminase

In enzymology, a D-4-hydroxyphenylglycine transaminase (EC 2.6.1.72) is an enzyme that catalyzes the chemical reaction

D-4-hydroxyphenylglycine + 2-oxoglutarate <math>\rightleftharpoons</math> 4-hydroxyphenylglyoxylate + L-glutamate

Thus, the two substrates of this enzyme are D-4-hydroxyphenylglycine and 2-oxoglutarate, whereas its two products are 4-hydroxyphenylglyoxylate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase. This enzyme is also called D-hydroxyphenylglycine aminotransferase. It employs one cofactor, pyridoxal phosphate.

References

• IUBMB entry for 2.6.1.72
• BRENDA references for 2.6.1.72 (Recommended.)
• PubMed references for 2.6.1.72
• PubMed Central references for 2.6.1.72
• Google Scholar references for 2.6.1.72
• Probst C, Grotz M, Krettek C, Pape HC (2005). "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. PMID 16525953.
• Probst C, Grotz M, Krettek C, Pape HC (2005). "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. PMID 16525953.

External links

The CAS registry number for this enzyme class is 117444-05-0.

• IUBMB entry for 2.6.1.72

• KEGG entry for 2.6.1.72

• BRENDA entry for 2.6.1.72

• NiceZyme view of 2.6.1.72

• EC2PDB: PDB structures for 2.6.1.72

• PRIAM entry for 2.6.1.72

• PUMA2 entry for 2.6.1.72

• IntEnz: Integrated Enzyme entry for 2.6.1.72

• MetaCyc entry for 2.6.1.72

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0047320: D-4-hydroxyphenylglycine transaminase

• AMIGO entry for GO code 0047320: D-4-hydroxyphenylglycine transaminase