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Inner ear illustration showing semicircular canal, hair cells, ampulla, cupula, vestibular nerve, & fluid
Latin cupula cochleae
Gray's subject #232 1051
Dorlands/Elsevier c_67/12271717

The cupula is a structure in the vestibular system, sensing proprioception.

The cupula is located within the ampullae of each of the three semicircular canals. As fluid rushes by the cupula, hair cells within it sense rotational acceleration, and transmit the corresponding signal to the brain through the vestibular nerve (CN VIII)

In their natural orientation within the head, the cupulae are located on the medial aspect of the semicircular canals. In this orientation, the kinocilia rest on the posterior aspect of the cupula.

Effects of alcohol

Further reading: Short-term effects of alcohol#vertigo

Alcohol causes vertigo by affecting the cupula; the cupula floats in a fluid called the endolymph which is the same density as that of blood. As alcohol dilutes blood in the cupula, the cupula becomes less dense and rises. The cupula is thus sensitized, and responds to movement by sending more action potentials to the brain, "confusing" it and causing the common disorientation associated with drunkenness.[1]

Other uses of cupula

Alternative use of cupula, i.e. as the apex of the cochlea. The cochlea and vestibule, viewed from above. (upula labeled at upper left.
  • There is also a structure in the cochlea called cupula, i.e. the apex of the cochlea.

The bony canal of the cochlea takes two and three-quarter turns around the modiolus. The modiolus is about 30 mm. in length, and diminishes gradually in diameter from the base to the summit, where it terminates in the cupula.

  • Another use of the term "cupula" is used to describe the cervical pleura in the thorax.
Illustration of otolith organs, showing another cupula, this time one of the layers.


External links

This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.