Cryptosporidiosis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Usama Talib, BSc, MD [2]

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Overview

The risk factors of cryptosporidiosis include malnutrition, HIV infection and unhygienic environments. Cryptosporidiosis can also affect cancer and transplant patients and those at risk of exposure to contaminated materials.[1][2]

Risk Factors

The risk factors for Cyptosporidiosis include:[1][3][4]

  • Malutrition
  • HIV
  • Immunocompromiszed individuals (can also occur in immunocompetent)
  • Unhygienic environments
  • Certain areas like
    • Sub-saharan Africa
  • Patients with inherited diseases of immune system
  • Cancer patients
  • Transplant patients
  • People with greater exposure to contaminated materials are more at risk for infection, such as:
    • Children who attend day care centers, including diaper-aged children
    • Child care workers
    • Parents of infected children
    • People who take care of other people with cryptosporidiosis
    • International travelers
    • Backpackers, hikers, and campers who drink unfiltered, untreated water
    • People who drink from untreated shallow, unprotected wells
    • People, including swimmers, who swallow water from contaminated sources
    • People who handle infected cattle
    • People exposed to human feces through sexual contact
    • Contaminated water may include water that has not been boiled or filtered, as well as contaminated recreational water sources. Several community-wide outbreaks of cryptosporidiosis have been linked to drinking municipal water or recreational water contaminated with Cryptosporidium.
  • Persons who are immunocompromised are at increased risks of having the diseases. Once infected, people with decreased immunity are most at risk for severe disease. The risk of developing severe disease may differ depending on each person's degree of immune suppression.

References

  1. 1.0 1.1 Dabas A, Shah D, Bhatnagar S, Lodha R (2017). "Epidemiology of Cryptosporidium in Pediatric Diarrheal Illnesses". Indian Pediatr. 54 (4): 299–309. PMID 28474590.
  2. Leitch GJ, He Q (2012). "Cryptosporidiosis-an overview". J Biomed Res. 25 (1): 1–16. doi:10.1016/S1674-8301(11)60001-8. PMC 3368497. PMID 22685452.
  3. Mor SM, Tzipori S (2008). "Cryptosporidiosis in children in Sub-Saharan Africa: a lingering challenge". Clin Infect Dis. 47 (7): 915–21. doi:10.1086/591539. PMC 2724762. PMID 18715159.
  4. Janoff EN, Reller LB (1987). "Cryptosporidium species, a protean protozoan". J Clin Microbiol. 25 (6): 967–75. PMC 269118. PMID 3298313.

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