Cefmenoxime

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Cefmenoxime
Systematic (IUPAC) name
(6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)- 2-methoxyimino-acetyl]amino}-3-[(1-methyltetrazol- 5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylic acid
Identifiers
CAS number	65085-01-0
ATC code	J01DD05
PubChem	5361486
DrugBank	APRD00851
Chemical data
Formula	C16H17N9O5S3
Mol. mass	511.562 g/mol
Pharmacokinetic data
Bioavailability	100% (given IM)
Protein binding	50% to 70%
Metabolism	Negligible
Half life	1 hour
Excretion	Renal, unchanged
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Intramuscular, intravenous

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Cefmenoxime is a third-generation cephalosporin antibiotic.

External links

• DDB 30892
• Yokota N, Koguchi M, Suzuki Y, Fukayama S, Ishihara R, Deguchi K, Oda S, Tanaka S, Nakane Y, Fukumoto T (1995). "Antibacterial activities of cefmenoxime against recent fresh clinical isolates from patients in sinusitis". Jpn J Antibiot 48 (5): 602-9. PMID 7637194.
• Paladino J, Fell R (1994). "Pharmacoeconomic analysis of cefmenoxime dual individualization in the treatment of nosocomial pneumonia.". Ann Pharmacother 28 (3): 384-9. PMID 8193431.
• Duncker G, Reich U, Krausse R (1994). "Cefmenoxime in corneal organ culture.". Ophthalmologica 208 (5): 262-6. PMID 7816419.

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