Calcitonin gene-related peptide receptor

	calcitonin receptor-like receptor
	Identifiers
Symbol	CALCRL
Entrez	10203
HUGO	16709
OMIM	114190
RefSeq	NM_005795
UniProt	Q16602
	Other data
Locus	Chr. 2 q21.1-21.3

The calcitonin gene-related peptide receptors consist of a 7-transmembrane G-protein coupled, calcitonin receptor-like receptor (CL) linked to one of three single transmembrane domain receptor activity-modifying proteins (RAMPs) that are essential for functional activity.

The association of CL with different RAMP proteins produces different receptors:

These receptors are linked to adenylate cyclase and activation results in the generation of intracellular cyclic adenosine monophosphate (cAMP).

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v • d • e Neuropeptide receptors
Hypothalamic hormone receptors	CRH - FSH - LHRH - TRH - Somatostatin
Pituitary hormone receptors	Vasopressin (1A, 1B, 2) - Oxytocin - LHCG - Type I cytokine receptor (GH, Prolactin) - TSH
Other hormone receptors	Atrial natriuretic factor - Calcitonin - Cholecystokinin (A, B) - VIP
Opioid receptors	Delta - Kappa - Mu - Sigma (1, 2) - Nociceptin
Other neuropeptide receptors	Angiotensin - Bradykinin (B1, B2) / Tachykinin (TACR1) - Calcitonin gene-related peptide - Galanin - GPCR neuropeptide (B/W, FF, S, Y) - Neurotensin

calcitonin receptor-like receptor
Identifiers
Symbol	CALCRL
Entrez	10203
HUGO	16709
OMIM	114190
RefSeq	NM_005795
UniProt	Q16602
Other data
Locus	Chr. 2 q21.1-21.3