CURE bleeding criteria

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

CURE Clinical Trials:

The Clopidogrel In Unstable Angina To Prevent Recurrent Events Trial

Clopidogrel In Unstable Angina To Prevent Recurrent Ischemic Events

“

Major Bleeding Life-threatening (fatal, intracranial, requiring surgical intervention, results in substantial hypotension requiring the use of intravenous inotropic agents) Hemoglobin decrease ≥5 g/dL or required ≥4 U of blood Other major bleeding Transfusion of 2–3 U, intraocular Minor Led to discontinuation of study drug

”