Biphenyl

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Biphenyl
200px
IUPAC name Biphenyl
Molecular formula C12H10
Molar mass 154.21 g/mol
CAS number 92-52-4
Density 1.04 g/cm3
Solubility Insoluble
Melting point

68.9 °C

Boiling point

256 °C

SMILES c1ccccc1(c2ccccc2)
Hazards
EU classification Irritant (Xi)
Dangerous for
the environment (N)
EU Index 601-042-00-8
NFPA 704

NFPA 704.svg

1
2
0
 
R-phrases R36/37/38,
S-phrases (S2), S23, S60, S61
Flash point 113 °C
Autoignition
temperature
540 °C
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references
File:Biphenyl 3D.png
CPK model of biphenyl showing its twisted conformation.

Biphenyl (or diphenyl or phenyl benzene or 1,1'-biphenyl or lemonene) is a solid organic compound that forms colorless to yellowish crystals. It has a distinctively pleasant smell. Biphenyl is an aromatic hydrocarbon with a molecular formula C12H10. Biphenyl is notable as a starting material for the production of polychlorinated biphenyls (PCBs), which were once widely used as dielectric fluids and heat transfer agents. Biphenyl is also an intermediate for the production of a host of other organic compounds such as emulsifiers, optical brighteners, crop protection products, and plastics.

Properties

Biphenyl occurs naturally in coal tar, crude oil, and natural gas and can be produced from these sources by distillation. Biphenyl is insoluble in water, but soluble in typical organic solvents. The biphenyl molecule consists of two connected benzene rings, without any additional functionalization, and is therefore not very reactive. The flashpoint is 113 °C and the autoignition temperature is 540 °C.

Stereochemistry

Rotation about the single bond in biphenyl, and especially its ortho-substituted derivatives, is sterically hindered. For this reason, some substituted biphenyls show atropisomerism; that is, the individual C2-symmetric-isomers are optically stable. Some derivatives, as well as related molecules such as BINAP, find application as ligands in asymmetric synthesis

Biological aspects

Biphenyl prevents the growth of molds and fungus, and is therefore used as a preservative (E230, in combination with E231, E232 and E233), particularly in the preservation of citrus fruits during transportation.

It is mildly toxic, but can be degraded biologically by conversion into nontoxic compounds. The ability to do so by adding oxygen molecules to the aromatic rings of biphenyl is found in some bacteria. It has been demonstrated that some bacteria that have degraded biphenyl can then also degrade polychlorinated biphenyls (PCBs), synthetic substances that are considerably more harmful to the environment than their natural counterparts. [1]

Biphenyl compounds

Substituted biphenyls can be prepared synthetically by various coupling reactions including the Suzuki reaction and the Ullmann reaction and have many uses. polychlorinated biphenyls are once used as cooling and insulating fluids and polybrominated biphenyls are flame retardants. The biphenyl motive also appears in drugs such as Valsartan and Telmisartan. The abbreviation E7 stands for a liquid crystal mixture consisting of several cyanobiphenyls with long aliphatic tails used commercially in liquid crystal displays.


References

  1. Biphenyl degradation - Streptomyces coelicolor, at GenomeNet Database

External links

fi:Bifenyyli


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