Beta-galactoside transacetylase

GAT in complex with CoA and two molecules/active site of IPTG viewed perpendicular to the molecular threefold axis of the enzyme

β-galactoside transacetylase is an enzyme that transfers an acetyl group from acetyl-CoA to β-galactosides. Coded by the gene (lacA) in the lac operon of Escherichia coli.^[1] Its precise function as part of the lac operon is not understood currently.^[2]

The kinetics of the enzyme were worked out in 1995.^[3]

References

↑ Wang XG; Olsen LR; Roderick SL. (Apr 2002). "Structure of the lac operon galactoside acetyltransferase". Structure 10 (4): 581-8. PMID 11937062.
↑ Roderick SL. (Jun 2005). "The lac operon galactoside acetyltransferase". C R Biol. 328 (6): 568-75. PMID 15950163.
↑ A. Lewendon; J. Ellis, W.V. Shaw (1995). "Structural and Mechanistic Studies of Galactoside Acetyltransferase, the Escherichia coli LacA Gene Product". J. Biol. Chem. 270: 26326-31.. PMID 7592843.

This transferase article is a stub. You can help WikiDoc by expanding it.

v • d • e Transferases: acyltransferases (EC 2.3)
2.3.1: other than amino-acyl groups (mostly acetyltransferases)	N-Acetylglutamate synthase - Choline acetyltransferase - Acetyl-Coenzyme A acetyltransferase - Dihydrolipoyl transacetylase - Acetyl-CoA C-acyltransferase - Beta-galactoside transacetylase - Carnitine O-palmitoyltransferase (CPT1, CPT2) - Acyltransferase like 2 - Chloramphenicol acetyltransferase - Aminolevulinic acid synthase - Beta-ketoacyl-ACP synthase - Glyceronephosphate O-acyltransferase - Lecithin-cholesterol acyltransferase - Histone acetyltransferase (P300/CBP) - Serotonin N-acetyl transferase
2.3.2 - Aminoacyltransferases	Gamma glutamyl transpeptidase - Peptidyl transferase - Transglutaminase (Tissue transglutaminase, Keratinocyte transglutaminase, Factor XIII)
2.3.3 - converted into alkyl on transfer	Citrate synthase - ATP citrate lyase - HMG-CoA synthase