Benjamin syndrome

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Benjamin Syndrome (or Benjamin anemia) is a type of multiple congenital anomaly/mental retardation (MCA/MR) syndrome. It is characterized by hypochromic anemia with mental deficiency and various craniofacial and other anomalies.

It was first described in the medical literature in 1911. Symptoms include megalocephaly, external ear deformities, dental caries, micromelia, hypoplastic bone deformities, hypogonadism, hypochromic anemia with occasional tumors, and mental and growth retardation.


  • Benjamin E. Über eine selbständige Form der Anämie im frühen Kindersalter. Verh Deut Ges Kinderh, 1911,119-24.
  • Benjamin syndrome via National Library of Medicine.

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